AUDACITY: A comprehensive approach for the detection and classification of Runs of Homozygosity in medical and population genomics
Runs of Homozygosity (RoHs) are popular among geneticists as the footprint of Bar Stools demographic processes, evolutionary forces and inbreeding in shaping our genome, and are known to confer risk of Mendelian and complex diseases.Notwithstanding growing interest in their study, there is unmet need for reliable and rapid methods for genomic analy